HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (2022)

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (1)
HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (2)
HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (3)

CLINICAL ANXIETY & DEPRESSION

HISTORICAL PERSPECTIVE

These are the most prevalent of mental disorders, 1/6 of all Americans suffer from anxiety and/or depression, only 50% of sufferers seek professional treatment

The costs run into $ Billions of healthcare dollars annually

Exists in all cultures and crosses all socio-economic lines

60% of all suicides in USA can be traced back to depression

Hindu writings dating back to 1500 BC detail anxiety and depression

The Old Testament describes King Saul’s severe depression and suicide

Ancients thought it was caused by evil spirits, they thought they could they would release them by drilling holes in the skull

There has been little progress in treatment for the past 1,700 years

Depression (from the latin verb deprimere, to press down)

The Birth of Neurotransmitters

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (4)

The human brain is extraordinarily complex:

Adult brain: 100 billion brain cells, with an average of 1,000 synaptic connections per cell

Every thought, action, and emotion involves communications between brain cells triggered by special chemicals called NEUROTRANSMITTERS

What Is A Neurotransmitter?

Neurotransmitters are chemicals signals that are released from a presynaptic nerve cell (sender) in the central nervous system into the synapse. The chemical signals bind to receptors on the postsynaptic neuron (or other type of receiving cell, such as muscle or gland). The type of receptor determines how the message is received and passed along.

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (5)

  • Neurotransmitters affect the whole body:
    • Mentally – concentration, focus, learning ability
    • Physically – sleep, cardiac function, metabolism/weight
    • Emotionally – mood, behavior, social attitude
    • They exist in the brain, intestines, spinal cord, peripheral nerves, and certain glands.

How Are Neurotransmitters Produced in the Body?

  • Most neurotransmitter production begins with an amino acid from the diet or from another chemical that is already present in the brain or intestines. Different amino acids are precursors for different neurotransmitters and the receptors they bind to.
  • Enzymes (genetic defects can stop production of these enzymes), SAMe and nutrients are required to convert the amino acid into the needed brain chemical.
  • B vitamins, along with minerals, vitamin D and others, play a critical role in brain health and in the manufacture of all your neurotransmitters.

By the mid 1970’s most scientific and medical experts agreed the dominant cause of most mental illness involved genetic or acquired chemical imbalances that alter brain functioning.

Psychiatry focus now was on:
Neurotransmitters, receptors and the molecular biology of the brain

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (6)

Digestive Dysfunction Impacts Body’s Ability to Utilize Nutrients

  • Impaired digestion makes it difficult for the body to convert protein/amino acids into neurotransmitters.
  • Even with adequate amounts of amino acids/protein consumed, poor digestion can hinder nutrient assimilation and absorption in the small intestine, leading to impaired ability to create neurotransmitters.
    • Poor digestive functioning may be caused by lack of proper enzymes and/or HCl levels, imbalance in gut flora, inflammation, and conditions like leaky gut, colitis, IBS.
    • Acid suppressors and proton pump inhibitors inhibit the body’s ability to properly break down protein, so these do not solve the problem!

Brief Overview of Common Neurotransmitters

  • Serotonin – Sleep cycle, depression, anxiety, PMS, temperature regulation, pain suppression, appetite
  • Dopamine – Focus, attention, memory, motivation, drive, mood, addictive disorders, voluntary movement
  • Norepinephrine – Energy, drive, stimulation, “fight or flight” response, insomnia, anxiety
  • Epinephrine – “Fight or Flight response”, metabolism, energy, depression, cognitive function
  • GABA – reduces excess stimulation
  • Glutamate – agitation, sleeplessness, depression when low

Measuring the Neurotransmitters

At the Natural Medicine Institute, we use:

Urine testing to measure the neurotransmitters

  • Simple urine test done in the privacy of your own home and then set to a lab for analysis

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (7)

  • Humans share 99.9% of their DNA; it’s the 0.1% that makes us different.
  • Our unique DNA determines our eye color, gender, ethnicity, and many physical and mental characteristics.
  • DNA differences also cause great variations in our innate biochemistry and our susceptibility to disease and illness including anxiety and depression.

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (8)

Research Database Findings

Laboratory testing of 30,000 mental health patients and controls.

  • More than 3 million lab assays for ADHD, Bipolar Disorder, anxiety, autism, depression, anxiety, schizophrenia or Alzheimer’s Disease and dementia.
  • > 2 million medical history factors.

“There are striking blood/urine chemistry differences between mental illness populations and the rest of society.”

Walsh WJ (2012). Nutrient Power. Skyhorse Publishing. New York, NY. CraytonJW, Walsh WJ (2007). J Trace Elements Med Biol. 21:17-21.

A Much Different Approach to the Treatment of Anxiety and Depression is the:

Nutrient Therapy Approach

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (9)

  • Extensive medical and mental health, family history
  • Lab testing of blood, urine, saliva
  • Diagnosis of metabolic and nutrient imbalances
  • Design of individualized nutrient treatment.
  • Pfeiffer’s Law: “For every drug that benefits a patient, there are natural substances that can achieve the same effect.”
  • More than 300 important nutrients in human biochemistry.
  • Some nutrients have powerful impacts on serotonin, dopamine, norepinephrine, GABA, and neurotransmission.
  • Our nutrient therapies focus on normalizing blood and brain levels of these nutrients.

The Good News

  • Nine nutrient imbalances dominate mental disorders,
  • These key nutrients are essential for either Neurotransmitter synthesis or regulation
  • Initial lab testing and clinical treatment focus on these factors.

High-Incidence Imbalances in Mental Disorders

Methylation Disorder

Zinc Depletion

Copper Overload

Folate Deficiency or Overload

Pyrrole Disorder

Toxic-Metal Overload

EPA, DHA, and/or AA Deficiency

The Power of Nutrients and their affects

  1. Neurotransmitter synthesis
  2. Epigenetic regulation of gene expression
  3. Influence Neurotransmitter reuptake processes
  4. Protection against oxidative stress

Magnesium found to treat DEPRESSION better than antidepressant drugs: New science

A breakthrough nutritional study conducted at theLarner College of Medicine at the University of Vermontand published in PLoS ONE has found that just 248mg of magnesium per day leads to anastounding reversal of depression symptomsin study subjects.*

Pyrrole disorder, also known as Pyroluria, or Mauve disorder:

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (10)

This is a urine test that checks for a biochemical imbalance involving an abnormality in hemoglobin synthesis that can be purely genetic or acquired through environmental and emotional stress and especially from dysbiosis & ‘leaky gut syndrome’ and the over use of antibiotics.

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (11)

  • Some persons are born with low levels of natural antioxidants like glutathione etc.
  • Illness, injury, or emotional trauma can produce oxidative stress.
  • Exposure to toxic metals, pesticides, and industrial pollutants increases oxidative stress.
  • Excessive oxidative stress has been observed in 95+ percent of mental disorder patients.
  • Most behavior, ADHD, anxiety, depression, and psychosis patients need strong antioxidant support.

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (12)

Fatty Acid Imbalance

More than 300 fats in the human body and brain. The brain is 80% fat (dry weight)

Saturated and unsaturated fats are especially important

Low Fat/No fat diet is a HUGE MISTAKE

Brain synapses- 4 fats make up 90% of the lipid content:

DHA (DOCOSAHEXANOIC ACID) DEFICIENCY: depression, ADHD, schizophrenia, dementia

EPA (EICOSAPENTANOIC ACID)

AA (ARACHIDONIC ACID)

DGLA (DIHOMO-GAMMA-LINOLEIC ACID)

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (13)

At the Natural Medicine Institute we use:

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (14)

The OnlyNutritional&FunctionalBrain HealthAssessment
Measurethe Health & Functionof the Brain & Nervous System

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (15)

Structural Brain Health Biomarkers

Omega-3 Index
Omega-6/3 Ratio
Trans Fat Index
Palmitic Acid Index

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (16)

FunctionalBrain Measurements

Focus/Attention
Memory
Processing Speed
Cognitive Flexibility

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (17)

Comprehensive NeuroHealthScore

Objective measurement of the health of your central nervous system with actionable results that empower improvement.

HEALTHY FAT AND CHOLESTEROL

Why Your Brain Needs Cholesterol & FAT

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (18)

BRAIN COMPOSITION
80% FAT (dry weight)
50% of 80 % is SATURATED FAT
25% of 80% IS CHOLESTEROL
YOUR BRAIN FUNCTIONS BETTER WITH FAT(KETONES) THAN GLUCOSE (SUGAR)

Numerous studies have linked low cholesterol with depression. One of the most recent found that women with low cholesterol are twice as likely to suffer from depression and anxiety. Researchers from Duke University Medical Center carried out personality trait measurements on 121 young women aged 18 to 27. They found that 39 percent of the women with low cholesterol levels scored high on personality traits that signaled proneness to depression, compared to 19 percent of women with normal or high levels of cholesterol.

Low Cholesterol Linked to Depression. BBC Online Network, May 25,1999.

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (19)

New Capability in Nutrient Therapy

  • Regulation of enzyme gene expression
  • Control of serotonin and dopamine reuptake
  • Improved antioxidant protection for the brain

Methylation

is the process of taking a single carbon and three hydrogens, known as a methyl group, and applying it to countless critical functions in your body such as: thinking, repairing DNA, turning on and off genes, fighting infections and getting rid of environmental toxins to name a few.

Almost every mass shooting over the last 20 years involved a shooter taking psychiatric drugs

Recent shootings in the news – Sandy Hook, The Batman Movie Shooting, Columbine, Virginia Tech, Las Vegas and others all have a common denominator: Prescription drugs were all in their systems at the times these crimes were committed.

“Stephen Paddock, who killed at least58 people and wounded hundreds morein Las Vegas on Sunday with high-powered rifles, was prescribed an anti-anxiety drug in June that can lead to aggressive behavior,” reports theLas Vegas Review-Journal:

Records from the Nevada Prescription Monitoring Program obtained Tuesday show Paddock was prescribed 50 10-milligram diazepam tablets by Henderson physician Dr. Steven Winkler on June 21.

Over 100 mass shooting events have been carried out by people who are taking psychiatric medications.

Carried out by students who had begun taking SSRI medications

The FDA has mandated that prescriptions for SSRI contain a warning that “antidepressants increase the risk of suicidal thinking and behavior”

Psychiatrists should perform a simple blood test prior to initiating SSRI therapy to identify low folate individuals at high risk for adverse side effects. Maybe these meds should be banned or more tightly regulated

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (24)

Individuals perpetrating unspeakable acts of violence is not a new phenomenon. What’s new, rather, are the altered states of consciousness induced by antidepressants and other psychotropic drugs well-documented to promote homicidal and suicidal behavior in susceptible individuals.

CHRONIC STRESS (anxiety/depression thyroid, adrenal, foods, infection etc.) can produce altered brain function:

NEGATIVE FEEDBACK LOOP

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (25)

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (26)

HEAL YOUR ANXIETY & DEPRESSION… NATURALLY - Dr. John A. Podlaski (27)

Clinical Depression Summary

  • Therapy using vitamins, minerals, amino acids, and other chemicals that are natural to the body (drug-free) are just as if not more effective
  • Separate treatment approach for each biotype of depression
  • Detox/cleanse, probiotics
  • LENS NEUROFEEDBACK THERAPY (90% effective)
  • 80% of families report major improvements and ability to eliminate psychiatric drugs.

Recommendation for Depression/anxiety

  • Test for metal-metabolism, pyrroles, methylation, toxic metals, essential fatty acid imbalances
  • Test for dysbiosis/leaky gut
  • Detoxification Cleanse
  • LENS NEUROFEEDBACK (>90% effective*)
  • Nutrient therapy to normalize biochemistry.
  • Regard drug medication as a last resort.

For further information and help with regard to treating your anxiety or depression naturally, please contact us at the Natural Medicine Institute 352.801.0021

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